Interrelationships of cold exposure and amino acid imbalances.

A moderate cold exposure has been used as a tool in inducing a higher food intake in experiments dealing with amino acid imbalances in the rat. The data indicate that the rats kept at 250 C suffer a severe metabolic disorder after ingesting amino acid imbalanced diets. In contrast, the animals kept at 70 C readily consumed the imbalanced diets and, consequently, grew as well as the controls. The activity of the glutamic-oxalacetic and the glutamicpyruvic transaminase were found to be increased as a result of a cold exposure. It is suggested that a moderate cold stress is an effective agent in correcting and overcoming amino acid imbalances.